A hotel in Milan doesn’t get more central than this: Park Hyatt Milano is just steps away from the cathedral, Galleria Vittorio Emanuele, and the shopping district. Housed in an 1870-era palazzo, this boutique hotel offers stylishly decorated rooms and public spaces kept in muted tones. The 29 ft. glass dome over the lobby lounge, named La Cupola, is a real eye-catcher: Here, guests are spoiled throughout the day with delicious drinks and Italian cuisine.