If the striking red plastic penguins standing watch over the main entrance are any indication, a stay at Louisville’s 21c Museum Hotel is anything but ordinary. The hotel complex, a mixture of converted bourbon and tobacco warehouses, features 9,000 square feet of gallery space that hosts rotating exhibitions of local and international art. The interiors are warm and lighthearted, each room decorated with original works of art, and stocked with organic Malin+Goetz bath products.